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Does replication groups scoring reduce false positive rate in SNP interaction discovery?
BACKGROUND: Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems. Present experimental studies typically use SNP arrays wi...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823693/ https://www.ncbi.nlm.nih.gov/pubmed/20092660 http://dx.doi.org/10.1186/1471-2164-11-58 |