Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease

BACKGROUND: The low-density lipoprotein receptor related protein 1 (LRP1) has been implicated in Alzheimer's disease (AD) but its signalling has not been fully evaluated. There is good evidence that the cytoplasmic domain of LRP1 is involved in protein-protein interactions, important in the cel...

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Detalles Bibliográficos
Autores principales: Kajiwara, Yuji, Franciosi, Sonia, Takahashi, Nagahide, Krug, Lisa, Schmeidler, James, Taddei, Kevin, Haroutunian, Vahram, Fried, Ulrik, Ehrlich, Michelle, Martins, Ralph N, Gandy, Samuel, Buxbaum, Joseph D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823744/
https://www.ncbi.nlm.nih.gov/pubmed/20205790
http://dx.doi.org/10.1186/1750-1326-5-1

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