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Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease

The presence of amyloid-β (Aβ) deposits in selected brain regions is a hallmark of Alzheimer's disease (AD). The amyloid deposits have "chaperone molecules" which play critical roles in amyloid formation and toxicity. We report here that treatment of rat hippocampal neurons with Aβ-ac...

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Detalles Bibliográficos
Autores principales:	Dinamarca, Margarita C, Sagal, Juan P, Quintanilla, Rodrigo A, Godoy, Juan A, Arrázola, Macarena S, Inestrosa, Nibaldo C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823746/ https://www.ncbi.nlm.nih.gov/pubmed/20205793 http://dx.doi.org/10.1186/1750-1326-5-4

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