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Therapeutic Efficacy of Human Hepatocyte Transplantation in a SCID/uPA Mouse Model with Inducible Liver Disease

BACKGROUND: Severe Combined Immune Deficient (SCID)/Urokinase-type Plasminogen Activator (uPA) mice undergo liver failure and are useful hosts for the propagation of transplanted human hepatocytes (HH) which must compete with recipient-derived hepatocytes for replacement of the diseased liver parenc...

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Detalles Bibliográficos
Autores principales: Douglas, Donna N., Kawahara, Toshiyasu, Sis, Banu, Bond, David, Fischer, Karl P., Tyrrell, D. Lorne J., Lewis, Jamie T., Kneteman, Norman M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823785/
https://www.ncbi.nlm.nih.gov/pubmed/20174638
http://dx.doi.org/10.1371/journal.pone.0009209