Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

The target of rapamycin (TOR) pathway is a major nutrient-sensing pathway that, when genetically downregulated, increases life span in evolutionarily diverse organisms including mammals. The central component of this pathway, TOR kinase, is the target of the inhibitory drug rapamycin, a highly speci...

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Detalles Bibliográficos
Autores principales: Bjedov, Ivana, Toivonen, Janne M., Kerr, Fiona, Slack, Cathy, Jacobson, Jake, Foley, Andrea, Partridge, Linda
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824086/
https://www.ncbi.nlm.nih.gov/pubmed/20074526
http://dx.doi.org/10.1016/j.cmet.2009.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824086/
https://www.ncbi.nlm.nih.gov/pubmed/20074526
http://dx.doi.org/10.1016/j.cmet.2009.11.010

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