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Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
The target of rapamycin (TOR) pathway is a major nutrient-sensing pathway that, when genetically downregulated, increases life span in evolutionarily diverse organisms including mammals. The central component of this pathway, TOR kinase, is the target of the inhibitory drug rapamycin, a highly speci...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824086/ https://www.ncbi.nlm.nih.gov/pubmed/20074526 http://dx.doi.org/10.1016/j.cmet.2009.11.010 |