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Phase II study of motesanib in Japanese patients with advanced gastrointestinal stromal tumors with prior exposure to imatinib mesylate
PURPOSE: Motesanib (AMG 706) is a multitargeted anticancer agent with an inhibitory action on the human vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and the cellular stem-cell factor receptor (KIT). The aim of this single-arm phase II clinical study was t...
Autores principales: | Sawaki, Akira, Yamada, Yasuhide, Komatsu, Yoshito, Kanda, Tatsuo, Doi, Toshihiko, Koseki, Masato, Baba, Hideo, Sun, Yu-Nien, Murakami, Koji, Nishida, Toshirou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824121/ https://www.ncbi.nlm.nih.gov/pubmed/19690858 http://dx.doi.org/10.1007/s00280-009-1103-9 |
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