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Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane
PURPOSE: Poly-(γ-l-glutamylglutamine)–paclitaxel (PGG–PTX) is a novel polymer-based formulation of paclitaxel (PTX) in which the PTX is linked to the polymer via ester bonds. PGG–PTX is of interest because it spontaneously forms very small nanoparticles in plasma. In mouse models, PGG–PTX increased...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824123/ https://www.ncbi.nlm.nih.gov/pubmed/19685054 http://dx.doi.org/10.1007/s00280-009-1099-1 |