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Theoretical and experimental analysis links isoform- specific ERK signalling to cell fate decisions

Cell fate decisions are regulated by the coordinated activation of signalling pathways such as the extracellular signal-regulated kinase (ERK) cascade, but contributions of individual kinase isoforms are mostly unknown. By combining quantitative data from erythropoietin-induced pathway activation in...

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Detalles Bibliográficos
Autores principales: Schilling, Marcel, Maiwald, Thomas, Hengl, Stefan, Winter, Dominic, Kreutz, Clemens, Kolch, Walter, Lehmann, Wolf D, Timmer, Jens, Klingmüller, Ursula
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824492/
https://www.ncbi.nlm.nih.gov/pubmed/20029368
http://dx.doi.org/10.1038/msb.2009.91