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GroEL dependency affects codon usage—support for a critical role of misfolding in gene evolution
It has recently been suggested that the use of optimal codons limits mistranslation-induced protein misfolding, yet evidence for this remains largely circumstantial. In contrast, molecular chaperones have long been recognized to play crucial roles in misfolding prevention and remedy. We propose that...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824523/ https://www.ncbi.nlm.nih.gov/pubmed/20087338 http://dx.doi.org/10.1038/msb.2009.94 |