Decoding pooled RNAi screens by means of barcode tiling arrays

BACKGROUND: RNAi screens via pooled short hairpin RNAs (shRNAs) have recently become a powerful tool for the identification of essential genes in mammalian cells. In the past years, several pooled large-scale shRNA screens have identified a variety of genes involved in cancer cell proliferation. All...

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Detalles Bibliográficos
Autores principales: Boettcher, Michael, Fredebohm, Johannes, Gholami, Amin Moghaddas, Hachmo, Yafit, Dotan, Iris, Canaani, Dan, Hoheisel, Jörg D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824726/
https://www.ncbi.nlm.nih.gov/pubmed/20051122
http://dx.doi.org/10.1186/1471-2164-11-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824726/
https://www.ncbi.nlm.nih.gov/pubmed/20051122
http://dx.doi.org/10.1186/1471-2164-11-7

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