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Decoding pooled RNAi screens by means of barcode tiling arrays
BACKGROUND: RNAi screens via pooled short hairpin RNAs (shRNAs) have recently become a powerful tool for the identification of essential genes in mammalian cells. In the past years, several pooled large-scale shRNA screens have identified a variety of genes involved in cancer cell proliferation. All...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824726/ https://www.ncbi.nlm.nih.gov/pubmed/20051122 http://dx.doi.org/10.1186/1471-2164-11-7 |