Proteasome Nuclear Activity Affects Chromosome Stability by Controlling the Turnover of Mms22, a Protein Important for DNA Repair

To expand the known spectrum of genes that maintain genome stability, we screened a recently released collection of temperature sensitive (Ts) yeast mutants for a chromosome instability (CIN) phenotype. Proteasome subunit genes represented a major functional group, and subsequent analysis demonstrat...

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Detalles Bibliográficos
Autores principales: Ben-Aroya, Shay, Agmon, Neta, Yuen, Karen, Kwok, Teresa, McManus, Kirk, Kupiec, Martin, Hieter, Philip
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824753/
https://www.ncbi.nlm.nih.gov/pubmed/20174551
http://dx.doi.org/10.1371/journal.pgen.1000852

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