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Numerical Modelling Of The V-J Combinations Of The T Cell Receptor TRA/TRD Locus
T-Cell antigen Receptor (TR) repertoire is generated through rearrangements of V and J genes encoding α and β chains. The quantification and frequency for every V-J combination during ontogeny and development of the immune system remain to be precisely established. We have addressed this issue by bu...
Autores principales: | Thuderoz, Florence, Simonet, Maria-Ana, Hansen, Olivier, Pasqual, Nicolas, Dariz, Aurélie, Baum, Thierry Pascal, Hierle, Vivien, Demongeot, Jacques, Marche, Patrice Noël, Jouvin-Marche, Evelyne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824756/ https://www.ncbi.nlm.nih.gov/pubmed/20174554 http://dx.doi.org/10.1371/journal.pcbi.1000682 |
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