The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule

Hepatitis C virus (HCV), a major cause of chronic liver disease in humans, is the focus of intense research efforts worldwide. Yet structural data on the viral envelope glycoproteins E1 and E2 are scarce, in spite of their essential role in the viral life cycle. To obtain more information, we develo...

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Detalles Bibliográficos
Autores principales: Krey, Thomas, d'Alayer, Jacques, Kikuti, Carlos M., Saulnier, Aure, Damier-Piolle, Laurence, Petitpas, Isabelle, Johansson, Daniel X., Tawar, Rajiv G., Baron, Bruno, Robert, Bruno, England, Patrick, Persson, Mats A. A., Martin, Annette, Rey, Félix A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824758/
https://www.ncbi.nlm.nih.gov/pubmed/20174556
http://dx.doi.org/10.1371/journal.ppat.1000762

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