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Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes
BACKGROUND: Aberrant activation of protein kinases is one of the essential oncogenic driving forces inherent to the process of tumorigenesis. The protein kinase CK2 plays an important role in diverse biological processes, including cell growth and proliferation as well as in the governing and transd...
Autores principales: | Mikula, Michal, Hanusek, Karolina, Paziewska, Agnieszka, Dzwonek, Artur, Rubel, Tymon, Bomsztyk, Karol, Ostrowski, Jerzy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824761/ https://www.ncbi.nlm.nih.gov/pubmed/20078881 http://dx.doi.org/10.1186/1471-2199-11-4 |
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