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Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes

BACKGROUND: Aberrant activation of protein kinases is one of the essential oncogenic driving forces inherent to the process of tumorigenesis. The protein kinase CK2 plays an important role in diverse biological processes, including cell growth and proliferation as well as in the governing and transd...

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Detalles Bibliográficos
Autores principales: Mikula, Michal, Hanusek, Karolina, Paziewska, Agnieszka, Dzwonek, Artur, Rubel, Tymon, Bomsztyk, Karol, Ostrowski, Jerzy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824761/
https://www.ncbi.nlm.nih.gov/pubmed/20078881
http://dx.doi.org/10.1186/1471-2199-11-4

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