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Formation of GW/P bodies as marker for microRNA-mediated regulation of innate immune signaling in THP-1 cells
GW bodies (GWB, or P bodies) are cytoplasmic foci thought to result from microRNA (miRNA) regulation of mRNA targets and subsequent mRNA degradation. The purpose of this study is to examine the effects of lipopolysaccharide (LPS) stimulation of human monocytes on GW body formation, miRNA induction,...
Autores principales: | Pauley, Kaleb M., Satoh, Minoru, Pauley, Brad A., Dominguez-Gutierrez, Paul R., Wallet, Shannon M., Holliday, L. Shannon, Cha, Seunghee, Reeves, Westley H., Chan, Edward K.L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824770/ https://www.ncbi.nlm.nih.gov/pubmed/19918258 http://dx.doi.org/10.1038/icb.2009.84 |
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