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Inhibitor of DNA Binding 3 Limits Development of Murine Slam-Associated Adaptor Protein-Dependent “Innate” γδ T cells

BACKGROUND: Id3 is a dominant antagonist of E protein transcription factor activity that is induced by signals emanating from the αβ and γδ T cell receptor (TCR). Mice lacking Id3 were previously shown to have subtle defects in positive and negative selection of TCRαβ(+) T lymphocytes. More recently...

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Detalles Bibliográficos
Autores principales: Verykokakis, Mihalis, Boos, Markus D., Bendelac, Albert, Adams, Erin J., Pereira, Pablo, Kee, Barbara L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824806/
https://www.ncbi.nlm.nih.gov/pubmed/20174563
http://dx.doi.org/10.1371/journal.pone.0009303