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Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics Approach
Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants. Virus diversity (the number of different viruses in a geographic region) was used to...
Autores principales: | Fumagalli, Matteo, Pozzoli, Uberto, Cagliani, Rachele, Comi, Giacomo P., Bresolin, Nereo, Clerici, Mario, Sironi, Manuela |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824813/ https://www.ncbi.nlm.nih.gov/pubmed/20174570 http://dx.doi.org/10.1371/journal.pgen.1000849 |
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