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Realtime PCR Is More Sensitive than Multiplex PCR for Diagnosis and Serotyping in Children with Culture Negative Pneumococcal Invasive Disease

BACKGROUND: Pneumococcal serotyping is usually performed by Quellung reaction, considered the gold standard test. However the method cannot be used on culture-negative samples. Molecular methods can be a useful alternative. The aim of the study was to evaluate the use of Multiplex-sequential-PCR (MS...

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Detalles Bibliográficos
Autores principales:	Azzari, Chiara, Moriondo, Maria, Indolfi, Giuseppe, Cortimiglia, Martina, Canessa, Clementina, Becciolini, Laura, Lippi, Francesca, de Martino, Maurizio, Resti, Massimo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824814/ https://www.ncbi.nlm.nih.gov/pubmed/20174571 http://dx.doi.org/10.1371/journal.pone.0009282

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