In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide

BACKGROUND: Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding pre-clinical testing using in vitro and ex vivo models. To validate our findings with on-going clinical trial results, we evaluated topical tenof...

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Detalles Bibliográficos
Autores principales: Rohan, Lisa C., Moncla, Bernard J., Kunjara Na Ayudhya, Ratiya Pamela, Cost, Marilyn, Huang, Yunda, Gai, Fang, Billitto, Nicole, Lynam, J. D., Pryke, Kara, Graebing, Phillip, Hopkins, Nicole, Rooney, James F., Friend, David, Dezzutti, Charlene S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824823/
https://www.ncbi.nlm.nih.gov/pubmed/20174579
http://dx.doi.org/10.1371/journal.pone.0009310

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