Roles of Electrostatics and Conformation in Protein-Crystal Interactions

In vitro studies have shown that the phosphoprotein osteopontin (OPN) inhibits the nucleation and growth of hydroxyapatite (HA) and other biominerals. In vivo, OPN is believed to prevent the calcification of soft tissues. However, the nature of the interaction between OPN and HA is not understood. I...

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Detalles Bibliográficos
Autores principales: Azzopardi, Paul V., O'Young, Jason, Lajoie, Gilles, Karttunen, Mikko, Goldberg, Harvey A., Hunter, Graeme K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824833/
https://www.ncbi.nlm.nih.gov/pubmed/20174473
http://dx.doi.org/10.1371/journal.pone.0009330

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