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Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells
Vascular smooth muscle cell (VSMC) proliferation remains a major cause of veno-arterial graft failure. We hypothesised that exposure of venous SMCs to arterial pressure would increase KLF5 expression and that of cell cycle genes. Porcine jugular veins were perfused at arterial or venous pressure in...
Autores principales: | Amirak, Emre, Zakkar, Mustafa, Evans, Paul C., Kemp, Paul R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824850/ https://www.ncbi.nlm.nih.gov/pubmed/19958749 http://dx.doi.org/10.1016/j.bbrc.2009.11.145 |
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