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PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs
BACKGROUND: Genetic association study is currently the primary vehicle for identification and characterization of disease-predisposing variant(s) which usually involves multiple single-nucleotide polymorphisms (SNPs) available. However, SNP-wise association tests raise concerns over multiple testing...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825231/ https://www.ncbi.nlm.nih.gov/pubmed/20100356 http://dx.doi.org/10.1186/1471-2156-11-6 |