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Carcinoid tumor of the verumontanum (colliculus seminalis) of the prostatic urethra with a coexisting prostatic adenocarcinoma: a case report

INTRODUCTION: Urethral carcinoid tumors are very rare tumors with only four cases described in the literature. CASE PRESENTATION: We present the case of a 61-year-old man with a primary carcinoid tumor of the verumontanum (colliculis seminalis) portion of the prostatic urethra with a coexisting pros...

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Detalles Bibliográficos
Autores principales: Smith, Maxwell, Lucia, M Scott, Werahera , Priya N, La Rosa, Francisco G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825242/
https://www.ncbi.nlm.nih.gov/pubmed/20205830
http://dx.doi.org/10.1186/1752-1947-4-16
Descripción
Sumario:INTRODUCTION: Urethral carcinoid tumors are very rare tumors with only four cases described in the literature. CASE PRESENTATION: We present the case of a 61-year-old man with a primary carcinoid tumor of the verumontanum (colliculis seminalis) portion of the prostatic urethra with a coexisting prostatic adenocarcinoma. In addition to whole mount hematoxylin and eosin staining, special immunoperoxidase staining specific for chromogranin A, neuron specific enolase, synaptophysin, pan-cytokeratin and PSA, and a special combined staining for racemase (α-methyl CoA) antigen and p63 antigen were performed. A review of the literature is included. A single focus of invasive prostatic adenocarcinoma was identified in the periphery of the mid-left, posterior quadrant of the prostate. Approximately 17 mm from this adenocarcinoma, within the verumontanum of the prostatic urethra, there was a 3 mm maximal dimension carcinoid tumor. CONCLUSION: Based on different histological features and antigenic profiles, we concluded that the two tumors were distinct.