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Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms

BACKGROUND: Retinoids, through their cognate nuclear receptors, exert potent effects on cell growth, differentiation and apoptosis, and have significant promise for cancer therapy and chemoprevention. These ligands can determine the ultimate fate of target cells by stimulating or repressing gene exp...

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Detalles Bibliográficos
Autores principales: Jiménez-Lara, Ana M, Aranda, Ana, Gronemeyer, Hinrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825243/
https://www.ncbi.nlm.nih.gov/pubmed/20102612
http://dx.doi.org/10.1186/1476-4598-9-15