Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage

BACKGROUND: CDC25B phosphatase is a cell cycle regulator that plays a critical role in checkpoint control. Up-regulation of CDC25B expression has been documented in a variety of human cancers, however, the relationships with the alteration of the molecular mechanisms that lead to oncogenesis still r...

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Detalles Bibliográficos
Autores principales: Bugler, Béatrix, Schmitt, Estelle, Aressy, Bernadette, Ducommun, Bernard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825247/
https://www.ncbi.nlm.nih.gov/pubmed/20128929
http://dx.doi.org/10.1186/1476-4598-9-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825247/
https://www.ncbi.nlm.nih.gov/pubmed/20128929
http://dx.doi.org/10.1186/1476-4598-9-29

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