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Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage
BACKGROUND: CDC25B phosphatase is a cell cycle regulator that plays a critical role in checkpoint control. Up-regulation of CDC25B expression has been documented in a variety of human cancers, however, the relationships with the alteration of the molecular mechanisms that lead to oncogenesis still r...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825247/ https://www.ncbi.nlm.nih.gov/pubmed/20128929 http://dx.doi.org/10.1186/1476-4598-9-29 |