Genetically Determined Measures of Striatal D2 Signaling Predict Prefrontal Activity during Working Memory Performance

BACKGROUND: Variation of the gene coding for D2 receptors (DRD2) has been associated with risk for schizophrenia and with working memory deficits. A functional intronic SNP (rs1076560) predicts relative expression of the two D2 receptors isoforms, D2S (mainly pre-synaptic) and D2L (mainly post-synap...

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Detalles Bibliográficos
Autores principales: Bertolino, Alessandro, Taurisano, Paolo, Pisciotta, Nicola Marco, Blasi, Giuseppe, Fazio, Leonardo, Romano, Raffaella, Gelao, Barbara, Bianco, Luciana Lo, Lozupone, Madia, Di Giorgio, Annabella, Caforio, Grazia, Sambataro, Fabio, Niccoli-Asabella, Artor, Papp, Audrey, Ursini, Gianluca, Sinibaldi, Lorenzo, Popolizio, Teresa, Sadee, Wolfgang, Rubini, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825256/
https://www.ncbi.nlm.nih.gov/pubmed/20179754
http://dx.doi.org/10.1371/journal.pone.0009348

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