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Human Multipotent Stromal Cells (MSCs) Increase Neurogenesis and Decrease Atrophy of the Striatum in a Transgenic Mouse Model for Huntington's Disease

BACKGROUND: Implantation of human multipotent stromal cells from bone marrow (hMSCs) into the dentate gyrus of the hippocampus of mice was previously shown to stimulate proliferation, migration and neural differentiation of endogenous neural stem cells. We hypothesized that hMSCs would be beneficial...

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Detalles Bibliográficos
Autores principales: Snyder, Brooke R., Chiu, Andrew M., Prockop, Darwin J., Chan, Anthony W. S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825266/
https://www.ncbi.nlm.nih.gov/pubmed/20179764
http://dx.doi.org/10.1371/journal.pone.0009347