Cargando…

Genetic Incorporation of Unnatural Amino Acids into Proteins in Mycobacterium tuberculosis

New tools are needed to study the intracellular pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), to facilitate new drug discovery and vaccine development. We have developed methodology to genetically incorporate unnatural amino acids into proteins in Mycobacterium...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Feng, Robbins, Scott, Guo, Jiantao, Shen, Weijun, Schultz, Peter G.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825273/ https://www.ncbi.nlm.nih.gov/pubmed/20179771 http://dx.doi.org/10.1371/journal.pone.0009354

Ejemplares similares

Editorial: Expansion of the Genetic Code: Unnatural Amino Acids and their Applications
por: Bag, Subhendu Sekhar, et al.
Publicado: (2022)

Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells
por: Nödling, Alexander R., et al.
Publicado: (2019)

Advances and Challenges in Cell-Free Incorporation of Unnatural Amino Acids Into Proteins
por: Gao, Wei, et al.
Publicado: (2019)

RF1 Knockout Allows Ribosomal Incorporation of Unnatural Amino Acids at Multiple Sites
por: Johnson, David B.F., et al.
Publicado: (2011)

Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs
por: Zhang, Haoran, et al.
Publicado: (2022)

Efficient Incorporation of Unnatural Amino Acids into Proteins with a Robust Cell-Free System
por: Gao, Wei, et al.
Publicado: (2019)

The Benefits of Unnatural Amino Acid Incorporation as Protein Labels for Single Molecule Localization Microscopy
por: Laxman, Pooja, et al.
Publicado: (2021)

Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid
por: Yu, Yang, et al.
Publicado: (2015)

Unnatural amino acid incorporation in E. coli: current and future applications in the design of therapeutic proteins
por: Wals, Kim, et al.
Publicado: (2014)

Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids
por: Drienovská, Ivana, et al.
Publicado: (2015)

Crucial Optimization of Translational Components towards Efficient Incorporation of Unnatural Amino Acids into Proteins in Mammalian Cells
por: Xiang, Liang, et al.
Publicado: (2013)

Genetic Code Engineering by Natural and Unnatural Base Pair Systems for the Site-Specific Incorporation of Non-Standard Amino Acids Into Proteins
por: Kimoto, Michiko, et al.
Publicado: (2022)

Modified Peptide Inhibitors of the Keap1–Nrf2 Protein–Protein Interaction Incorporating Unnatural Amino Acids
por: Georgakopoulos, Nikolaos D., et al.
Publicado: (2018)

Reprogramming natural proteins using unnatural amino acids
por: Adhikari, Anup, et al.
Publicado: (2021)

Site-Specific Incorporation of Unnatural Amino Acids into Escherichia coli Recombinant Protein: Methodology Development and Recent Achievement
por: Smolskaya, Sviatlana, et al.
Publicado: (2019)

Fine-tuning Interaction between Aminoacyl-tRNA Synthetase and tRNA for Efficient Synthesis of Proteins Containing Unnatural Amino Acids
por: Wang, Nanxi, et al.
Publicado: (2014)

Tunable translational control using site-specific unnatural amino acid incorporation in Escherichia coli
por: Kato, Yusuke
Publicado: (2015)

Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification
por: Rowan, Fiona C., et al.
Publicado: (2013)

A linear DNA template-based framework for site-specific unnatural amino acid incorporation
por: Chen, Xinjie, et al.
Publicado: (2021)

Studies on the Incorporation of an Unnatural Amino Acid, p-DI-(2-Hydroxy[(14)C(2)]Ethyl) Amino-L-Phenylalanine, into Proteins
por: Brookes, P.
Publicado: (1959)

Site-Specific Labeling of Proteins Using Unnatural Amino Acids
por: Lee, Kyung Jin, et al.
Publicado: (2019)

P19-09. Site-specific incorporation of an unnatural amino acid into the HIV-1 Env spike
por: Arnett, SO, et al.
Publicado: (2009)

Reinitiation at non-canonical start codons leads to leak expression when incorporating unnatural amino acids
por: Kalstrup, Tanja, et al.
Publicado: (2015)

Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction
por: Zhao, Hongxia, et al.
Publicado: (2021)

Toward efficient multiple-site incorporation of unnatural amino acids using cell-free translation system
por: Hou, Jiaqi, et al.
Publicado: (2021)

A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells
por: Ge, Yun, et al.
Publicado: (2016)

Enhanced Yield of Recombinant Proteins with Site-Specifically Incorporated Unnatural Amino Acids Using a Cell-Free Expression System
por: Smolskaya, Sviatlana, et al.
Publicado: (2013)

Evaluation and optimisation of unnatural amino acid incorporation and bioorthogonal bioconjugation for site-specific fluorescent labelling of proteins expressed in mammalian cells
por: Jakob, Leonhard, et al.
Publicado: (2018)

Unnatural amino acids: better than the real things?
por: Minnihan, Ellen C, et al.
Publicado: (2009)

Exploring the role of unnatural amino acids in antimicrobial peptides
por: Oliva, Rosario, et al.
Publicado: (2018)

Synthesis of complex unnatural fluorine-containing amino acids
por: Brittain, William D.G., et al.
Publicado: (2020)

A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids
por: Ieong, Ka-Weng, et al.
Publicado: (2014)

Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR
por: Yang, Fan, et al.
Publicado: (2015)

Development of a Novel Q-body Using an In Vivo Site-Specific Unnatural Amino Acid Incorporation System
por: Kurumida, Yoichi, et al.
Publicado: (2018)

FRI162 Ligand-dependent Photocrosslinking of Mineralocorticoid Receptors Using Site-directed Incorporation of Unnatural Amino Acids
por: Almeida-Prieto, Brian, et al.
Publicado: (2023)

Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair
por: Hancock, Susan M., et al.
Publicado: (2010)

Conditional knockout tools: Application of site-specific incorporation of unnatural amino acid via genetic code expansion in viral and parasite vaccine development
por: Liu, Pinghua, et al.
Publicado: (2017)

Fluorescence Modulation of Green Fluorescent Protein Using Fluorinated Unnatural Amino Acids
por: Villa, Jordan K., et al.
Publicado: (2017)

Pyrrolysine-Inspired in Cellulo Synthesis of an Unnatural Amino Acid for Facile Macrocyclization of Proteins
por: Tai, Jingxuan, et al.
Publicado: (2023)

Study and design of amino acid-based radical enzymes using unnatural amino acids
por: Yuan, Feiyan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9usvbepgsvmg376tfmvlv5tk9c