Combining the in vivo comet and micronucleus assays: a practical approach to genotoxicity testing and data interpretation

Despite regulatory directives requiring the reduction of animal use in safety testing, recent modifications to genotoxicity testing guidelines now propose the use of two in vivo genotoxicity assays as a follow-up to an in vitro positive (International Conference on Harmonization Consensus Draft Guid...

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Detalles Bibliográficos
Autor principal: Vasquez, Marie Z.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825345/
https://www.ncbi.nlm.nih.gov/pubmed/19969526
http://dx.doi.org/10.1093/mutage/gep060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825345/
https://www.ncbi.nlm.nih.gov/pubmed/19969526
http://dx.doi.org/10.1093/mutage/gep060

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