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Heart-specific Deletion of CnB1 Reveals Multiple Mechanisms Whereby Calcineurin Regulates Cardiac Growth and Function
Calcineurin is a protein phosphatase that is uniquely regulated by sustained increases in intracellular Ca(2+) following signal transduction events. Calcineurin controls cellular proliferation, differentiation, apoptosis, and inducible gene expression following stress and neuroendocrine stimulation....
Autores principales: | Maillet, Marjorie, Davis, Jennifer, Auger-Messier, Mannix, York, Allen, Osinska, Hanna, Piquereau, Jérôme, Lorenz, John N., Robbins, Jeffrey, Ventura-Clapier, Renée, Molkentin, Jeffery D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825466/ https://www.ncbi.nlm.nih.gov/pubmed/20037164 http://dx.doi.org/10.1074/jbc.M109.056143 |
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