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Doppel and PrP(C) co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells

Dpl (doppel) is a paralogue of the PrP(C) (cellular prion protein), whose misfolded conformer (the scrapie prion protein, PrP(Sc)) is responsible for the onset of TSEs (transmissible spongiform encephalopathies) or prion diseases. It has been shown that the ectopic expression of Dpl in the brains of...

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Detalles Bibliográficos
Autores principales:	Caputo, Anna, Sarnataro, Daniela, Campana, Vincenza, Costanzo, Maddalena, Negro, Alessandro, Sorgato, M. Catia, Zurzolo, Chiara
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825736/ https://www.ncbi.nlm.nih.gov/pubmed/19888917 http://dx.doi.org/10.1042/BJ20091050

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