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BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer
In sporadic epithelial ovarian cancer (EOC), the inactivation of BRCA1 through various mechanisms is a relatively common event. BRCA1 protein dysfunction results in the breakdown of various critical pathways in the cell, notably, the DNA damage response and repair pathway. Tumors from patients with...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825770/ https://www.ncbi.nlm.nih.gov/pubmed/20182637 http://dx.doi.org/10.1155/2010/891059 |