TGF-β signalling is regulated by Schnurri-2 dependent nuclear translocation of CLIC4 and consequent stabilization of phospho Smad2–3

CLIC4, a multifunctional protein that traffics between the cytoplasm and nucleus, interacts with Schnurri-2, a transcription factor in the BMP pathway. TGF-β enhances the expression of both CLIC4 and Schnurri-2 and promotes their association in the cytoplasm and their translocation to the nucleus. I...

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Detalles Bibliográficos
Autores principales: Shukla, Anjali, Malik, Mariam, Cataisson, Christophe, Ho, Yan, Friesen, Travis, Suh, Kwang S., Yuspa, Stuart H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825893/
https://www.ncbi.nlm.nih.gov/pubmed/19448624
http://dx.doi.org/10.1038/ncb1885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825893/
https://www.ncbi.nlm.nih.gov/pubmed/19448624
http://dx.doi.org/10.1038/ncb1885

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