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Interferon-induced Sus scrofa Mx1 blocks endocytic traffic of incoming influenza A virus particles

The interferon-induced Mx proteins of vertebrates are dynamin-like GTPases, some isoforms of which can additionally inhibit the life cycle of certain RNA viruses. Here we show that the porcine Mx1 protein (poMx1) inhibits replication of influenza A virus and we attempt to identify the step at which...

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Detalles Bibliográficos
Autores principales: Palm, Mélanie, Garigliany, Mutien-Marie, Cornet, François, Desmecht, Daniel
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826089/
https://www.ncbi.nlm.nih.gov/pubmed/20167191
http://dx.doi.org/10.1051/vetres/2010001