Cargando…

Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes

How does the brain process incoming information and produce thoughts? These questions represent, to all likelihood, the most challenging matters ever faced by natural sciences, matters which may never be fully comprehended. The evolution of the nervous system that, in about billion of years, brought...

Descripción completa

Detalles Bibliográficos
Autor principal: Verkhratsky, Alexei
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826102/
https://www.ncbi.nlm.nih.gov/pubmed/19909235
http://dx.doi.org/10.1042/AN20090049
_version_ 1782177839592767488
author Verkhratsky, Alexei
author_facet Verkhratsky, Alexei
author_sort Verkhratsky, Alexei
collection PubMed
description How does the brain process incoming information and produce thoughts? These questions represent, to all likelihood, the most challenging matters ever faced by natural sciences, matters which may never be fully comprehended. The evolution of the nervous system that, in about billion of years, brought into existence the human brain progressed through an ever-increasing complexity of neural networks. This evolution began from the diffuse nervous system, in which primordial neurons were able to sense the environmental inputs and convey them to effector organs and to the neighbouring neurons. At the next evolutionary stage the conglomerates of neuronal cell bodies, the ganglia, appeared, thus forming the primitive centralized nervous system. The developments which ensued went through a continuous increase in complexity of neuronal conglomerates, which eventually formed the central nervous system, which attained maximal perfection in mammals. In this issue of ASN NEURO, Osborne et al. have described details of real-time imaging of cannabinoid receptor trafficking in astrocytes, a technique that will help to elucidate the role of these receptors in the ever-increasing complex neural networks.
format Text
id pubmed-2826102
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher American Society for Neurochemistry
record_format MEDLINE/PubMed
spelling pubmed-28261022010-03-02 Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes Verkhratsky, Alexei ASN Neuro Commentary How does the brain process incoming information and produce thoughts? These questions represent, to all likelihood, the most challenging matters ever faced by natural sciences, matters which may never be fully comprehended. The evolution of the nervous system that, in about billion of years, brought into existence the human brain progressed through an ever-increasing complexity of neural networks. This evolution began from the diffuse nervous system, in which primordial neurons were able to sense the environmental inputs and convey them to effector organs and to the neighbouring neurons. At the next evolutionary stage the conglomerates of neuronal cell bodies, the ganglia, appeared, thus forming the primitive centralized nervous system. The developments which ensued went through a continuous increase in complexity of neuronal conglomerates, which eventually formed the central nervous system, which attained maximal perfection in mammals. In this issue of ASN NEURO, Osborne et al. have described details of real-time imaging of cannabinoid receptor trafficking in astrocytes, a technique that will help to elucidate the role of these receptors in the ever-increasing complex neural networks. American Society for Neurochemistry 2009-12-08 /pmc/articles/PMC2826102/ /pubmed/19909235 http://dx.doi.org/10.1042/AN20090049 Text en © 2009 The Author(s). http://creativecommons.org/licenses/by-nc/2.5/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commerical use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Verkhratsky, Alexei
Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
title Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
title_full Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
title_fullStr Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
title_full_unstemmed Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
title_short Filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
title_sort filming the glial dreams: real-time imaging of cannabinoid receptor trafficking in astrocytes
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826102/
https://www.ncbi.nlm.nih.gov/pubmed/19909235
http://dx.doi.org/10.1042/AN20090049
work_keys_str_mv AT verkhratskyalexei filmingtheglialdreamsrealtimeimagingofcannabinoidreceptortraffickinginastrocytes