Rac1 and Cdc42 are regulators of HRas(V12)-transformation and angiogenic factors in human fibroblasts

BACKGROUND: The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GTPases in HRas-mediated tr...

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Detalles Bibliográficos
Autores principales: Appledorn, Daniel M, Dao, Kim-Hien T, O'Reilly, Sandra, Maher, Veronica M, McCormick, J Justin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826294/
https://www.ncbi.nlm.nih.gov/pubmed/20067638
http://dx.doi.org/10.1186/1471-2407-10-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826294/
https://www.ncbi.nlm.nih.gov/pubmed/20067638
http://dx.doi.org/10.1186/1471-2407-10-13

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