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Rac1 and Cdc42 are regulators of HRas(V12)-transformation and angiogenic factors in human fibroblasts
BACKGROUND: The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GTPases in HRas-mediated tr...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826294/ https://www.ncbi.nlm.nih.gov/pubmed/20067638 http://dx.doi.org/10.1186/1471-2407-10-13 |