Cargando…
Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons
BACKGROUND: Septal cholinergic neurons account for most of the cholinergic innervations of the hippocampus, playing a key role in the regulation of hippocampal synaptic activity. Disruption of the septo-hippocampal pathway by an experimental transection of the fimbria-fornix drastically reduces the...
Autores principales: | Lazo, Oscar M, Mauna, Jocelyn C, Pissani, Claudia A, Inestrosa, Nibaldo C, Bronfman, Francisca C |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826326/ https://www.ncbi.nlm.nih.gov/pubmed/20205865 http://dx.doi.org/10.1186/1750-1326-5-5 |
Ejemplares similares
-
Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease
por: Cabeza, Carolina, et al.
Publicado: (2012) -
BMP9 Protects Septal Neurons from Axotomy-Evoked Loss of Cholinergic Phenotype
por: Lopez-Coviella, Ignacio, et al.
Publicado: (2011) -
hNGF Peptides Elicit the NGF-TrkA Signalling Pathway in Cholinergic Neurons and Retain Full Neurotrophic Activity in the DRG Assay
por: Triaca, Viviana, et al.
Publicado: (2020) -
Death Commitment Point Is Advanced by Axotomy in Sympathetic Neurons
por: Fletcher, Graham C., et al.
Publicado: (2000) -
c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation
por: Palmada, M., et al.
Publicado: (2002)