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The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms

BACKGROUND: Despite its role as a generator of haplotypic variation, little is known about how the rates of recombination evolve across taxa. Recombination is a very labile force, susceptible to evolutionary and life trait related processes, which have also been correlated with general levels of gen...

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Autores principales: Jaramillo-Correa, Juan P, Verdú, Miguel, González-Martínez, Santiago C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826329/
https://www.ncbi.nlm.nih.gov/pubmed/20100325
http://dx.doi.org/10.1186/1471-2148-10-22
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author Jaramillo-Correa, Juan P
Verdú, Miguel
González-Martínez, Santiago C
author_facet Jaramillo-Correa, Juan P
Verdú, Miguel
González-Martínez, Santiago C
author_sort Jaramillo-Correa, Juan P
collection PubMed
description BACKGROUND: Despite its role as a generator of haplotypic variation, little is known about how the rates of recombination evolve across taxa. Recombination is a very labile force, susceptible to evolutionary and life trait related processes, which have also been correlated with general levels of genetic diversity. For example, in plants, it has been shown that long-lived outcrossing taxa, such as trees, have higher heterozygosity (H(e)) at SSRs and allozymes than selfing or annual species. However, some of these tree taxa have surprisingly low levels of nucleotide diversity at the DNA sequence level, which points to recombination as a potential generator of genetic diversity in these organisms. In this study, we examine how genome-wide and within-gene rates of recombination evolve across plant taxa, determine whether such rates are influenced by the life-form adopted by species, and evaluate if higher genome-wide rates of recombination translate into higher H(e )values, especially in trees. RESULTS: Estimates of genome-wide (cM/Mb) recombination rates from 81 higher plants showed a significant phylogenetic signal. The use of different comparative phylogenetic models demonstrated that there is a positive correlation between recombination rate and H(e )(0.83 ± 0.29), and that trees have higher rates of genome-wide recombination than short-lived herbs and shrubs. A significant taxonomic component was further made evident by our models, as conifers exhibited lower recombination rates than angiosperms. This trend was also found at the within-gene level. CONCLUSIONS: Altogether, our results illustrate how both common ancestry and life-history traits have to be taken into account for understanding the evolution of genetic diversity and genomic rates of recombination across plant species, and highlight the relevance of species life forms to explain general levels of diversity and recombination.
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spelling pubmed-28263292010-02-23 The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms Jaramillo-Correa, Juan P Verdú, Miguel González-Martínez, Santiago C BMC Evol Biol Research article BACKGROUND: Despite its role as a generator of haplotypic variation, little is known about how the rates of recombination evolve across taxa. Recombination is a very labile force, susceptible to evolutionary and life trait related processes, which have also been correlated with general levels of genetic diversity. For example, in plants, it has been shown that long-lived outcrossing taxa, such as trees, have higher heterozygosity (H(e)) at SSRs and allozymes than selfing or annual species. However, some of these tree taxa have surprisingly low levels of nucleotide diversity at the DNA sequence level, which points to recombination as a potential generator of genetic diversity in these organisms. In this study, we examine how genome-wide and within-gene rates of recombination evolve across plant taxa, determine whether such rates are influenced by the life-form adopted by species, and evaluate if higher genome-wide rates of recombination translate into higher H(e )values, especially in trees. RESULTS: Estimates of genome-wide (cM/Mb) recombination rates from 81 higher plants showed a significant phylogenetic signal. The use of different comparative phylogenetic models demonstrated that there is a positive correlation between recombination rate and H(e )(0.83 ± 0.29), and that trees have higher rates of genome-wide recombination than short-lived herbs and shrubs. A significant taxonomic component was further made evident by our models, as conifers exhibited lower recombination rates than angiosperms. This trend was also found at the within-gene level. CONCLUSIONS: Altogether, our results illustrate how both common ancestry and life-history traits have to be taken into account for understanding the evolution of genetic diversity and genomic rates of recombination across plant species, and highlight the relevance of species life forms to explain general levels of diversity and recombination. BioMed Central 2010-01-25 /pmc/articles/PMC2826329/ /pubmed/20100325 http://dx.doi.org/10.1186/1471-2148-10-22 Text en Copyright ©2010 Jaramillo-Correa et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research article
Jaramillo-Correa, Juan P
Verdú, Miguel
González-Martínez, Santiago C
The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
title The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
title_full The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
title_fullStr The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
title_full_unstemmed The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
title_short The contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
title_sort contribution of recombination to heterozygosity differs among plant evolutionary lineages and life-forms
topic Research article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826329/
https://www.ncbi.nlm.nih.gov/pubmed/20100325
http://dx.doi.org/10.1186/1471-2148-10-22
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