Cancer cell sensitivity to bortezomib is associated with survivin expression and p53 status but not cancer cell types

BACKGROUND: Survivin is known playing a role in drug resistance. However, its role in bortezomib-mediated inhibition of growth and induction of apoptosis is unclear. There are conflicting reports for the effect of bortezomib on survivin expression, which lacks of a plausible explanation. Methods: In...

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Detalles Bibliográficos
Autores principales: Ling, Xiang, Calinski, Diane, Chanan-Khan, Asher A, Zhou, Muxiang, Li, Fengzhi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826345/
https://www.ncbi.nlm.nih.gov/pubmed/20096120
http://dx.doi.org/10.1186/1756-9966-29-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826345/
https://www.ncbi.nlm.nih.gov/pubmed/20096120
http://dx.doi.org/10.1186/1756-9966-29-8

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