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Cancer cell sensitivity to bortezomib is associated with survivin expression and p53 status but not cancer cell types
BACKGROUND: Survivin is known playing a role in drug resistance. However, its role in bortezomib-mediated inhibition of growth and induction of apoptosis is unclear. There are conflicting reports for the effect of bortezomib on survivin expression, which lacks of a plausible explanation. Methods: In...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826345/ https://www.ncbi.nlm.nih.gov/pubmed/20096120 http://dx.doi.org/10.1186/1756-9966-29-8 |