Neurotoxic Manifestations of an Overdose Intrathecal Injection of Gadopentetate Dimeglumine

The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection...

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Detalles Bibliográficos
Autores principales: Park, Kwan-Woong, Im, Soo-Bin, Kim, Bum-Tae, Hwang, Sun-Chul, Park, Jong-Sun, Shin, Won-Han
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826734/
https://www.ncbi.nlm.nih.gov/pubmed/20191058
http://dx.doi.org/10.3346/jkms.2010.25.3.505
Descripción
Sumario:The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection presenting with neurotoxic manifestations, including a decreased level of consciousness, global aphasia, rigidity, and visual disturbance.

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