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Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report

Metastatic involement of penis is an exceptionally rare condition. 77% of the metastases are originated from the pelvic region; prostate and bladder are the most frequent primary locations. Retrograde venous route, retrograde lymphatic route, arterial spread, direct extension, implantation and secon...

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Autores principales: Sönmez, Nurettin Cem, Coşkun, Burhan, Arisan, Serdar, Güney, Soner, Dalkılıç, Ayhan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827083/
https://www.ncbi.nlm.nih.gov/pubmed/20184686
http://dx.doi.org/10.4076/1757-1626-2-7281
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author Sönmez, Nurettin Cem
Coşkun, Burhan
Arisan, Serdar
Güney, Soner
Dalkılıç, Ayhan
author_facet Sönmez, Nurettin Cem
Coşkun, Burhan
Arisan, Serdar
Güney, Soner
Dalkılıç, Ayhan
author_sort Sönmez, Nurettin Cem
collection PubMed
description Metastatic involement of penis is an exceptionally rare condition. 77% of the metastases are originated from the pelvic region; prostate and bladder are the most frequent primary locations. Retrograde venous route, retrograde lymphatic route, arterial spread, direct extension, implantation and secondary to instrumentation are the mechanisms of metastasis. Approximately two thirds of all penile metastasis are detected at a mean time of 18 months after the detection of the primary tumor and the remaining one third is presented at the same time with primary tumor. Diagnosis is usually made by biopsy and also non invasive methods as MRI or colour-coded duplex ultrasonography. Treatment options in these patients are local excision, partial or complete penectomy, external beam radiation therapy and chemotheraphy. Despite these alternatives prognosis is usually poor. We present a case of urethelial carcinoma of the bladder and coincidental prostate adenocarcinoma with penile metastasis which is presented with priapism 6 months after radical cystectomy as the first systemic manifestation. We performed biopsy initially for staging and the patient underwent MRI showing the extension of the disease. The patient underwent radiotherapy of 56 gy and priapism partially resolved after the treatment. Chemotheraphy was also planned but the patient died 3 months following radiotheraphy.
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spelling pubmed-28270832010-02-24 Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report Sönmez, Nurettin Cem Coşkun, Burhan Arisan, Serdar Güney, Soner Dalkılıç, Ayhan Cases J Case report Metastatic involement of penis is an exceptionally rare condition. 77% of the metastases are originated from the pelvic region; prostate and bladder are the most frequent primary locations. Retrograde venous route, retrograde lymphatic route, arterial spread, direct extension, implantation and secondary to instrumentation are the mechanisms of metastasis. Approximately two thirds of all penile metastasis are detected at a mean time of 18 months after the detection of the primary tumor and the remaining one third is presented at the same time with primary tumor. Diagnosis is usually made by biopsy and also non invasive methods as MRI or colour-coded duplex ultrasonography. Treatment options in these patients are local excision, partial or complete penectomy, external beam radiation therapy and chemotheraphy. Despite these alternatives prognosis is usually poor. We present a case of urethelial carcinoma of the bladder and coincidental prostate adenocarcinoma with penile metastasis which is presented with priapism 6 months after radical cystectomy as the first systemic manifestation. We performed biopsy initially for staging and the patient underwent MRI showing the extension of the disease. The patient underwent radiotherapy of 56 gy and priapism partially resolved after the treatment. Chemotheraphy was also planned but the patient died 3 months following radiotheraphy. BioMed Central 2009-08-14 /pmc/articles/PMC2827083/ /pubmed/20184686 http://dx.doi.org/10.4076/1757-1626-2-7281 Text en Copyright ©2009 Sönmez et al.; licensee Cases Network Ltd. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case report
Sönmez, Nurettin Cem
Coşkun, Burhan
Arisan, Serdar
Güney, Soner
Dalkılıç, Ayhan
Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
title Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
title_full Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
title_fullStr Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
title_full_unstemmed Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
title_short Early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
title_sort early penile metastasis from primary bladder cancer as the first systemic manifestation: a case report
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827083/
https://www.ncbi.nlm.nih.gov/pubmed/20184686
http://dx.doi.org/10.4076/1757-1626-2-7281
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