Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report

We report a case of chronic lymphocytic leukemia with a characteristic cytogenetics finding detected by fluorescent in situ hybridization. This case has deletion in p53 gene in 50% of interphase nuclei studied in the peripheral blood and polyploidy in 30% of cells. To our knowledge polyploidy is not...

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Detalles Bibliográficos
Autores principales: Eid, Maha, Kayed, Hesham, El-Bassyouni, Hala T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827117/
https://www.ncbi.nlm.nih.gov/pubmed/20184701
http://dx.doi.org/10.4076/1757-1626-2-8872
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author Eid, Maha
Kayed, Hesham
El-Bassyouni, Hala T
author_facet Eid, Maha
Kayed, Hesham
El-Bassyouni, Hala T
author_sort Eid, Maha
collection PubMed
description We report a case of chronic lymphocytic leukemia with a characteristic cytogenetics finding detected by fluorescent in situ hybridization. This case has deletion in p53 gene in 50% of interphase nuclei studied in the peripheral blood and polyploidy in 30% of cells. To our knowledge polyploidy is not commonly reported with chronic lymphocytic leukemia patients.
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spelling pubmed-28271172010-02-24 Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report Eid, Maha Kayed, Hesham El-Bassyouni, Hala T Cases J Case Report We report a case of chronic lymphocytic leukemia with a characteristic cytogenetics finding detected by fluorescent in situ hybridization. This case has deletion in p53 gene in 50% of interphase nuclei studied in the peripheral blood and polyploidy in 30% of cells. To our knowledge polyploidy is not commonly reported with chronic lymphocytic leukemia patients. BioMed Central 2009-09-11 /pmc/articles/PMC2827117/ /pubmed/20184701 http://dx.doi.org/10.4076/1757-1626-2-8872 Text en Copyright ©2009 Eid et al.; licensee Cases Network Ltd. licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Eid, Maha
Kayed, Hesham
El-Bassyouni, Hala T
Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
title Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
title_full Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
title_fullStr Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
title_full_unstemmed Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
title_short Polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
title_sort polyploidy in chronic lymphocytic leukemia with p53 deletion detected by fish: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827117/
https://www.ncbi.nlm.nih.gov/pubmed/20184701
http://dx.doi.org/10.4076/1757-1626-2-8872
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