Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports

Genotype 4 Hepatitis C virus represents approximately 20% of global Hepatitis C virus infection and is the source of a considerable burden to health-care providers across the globe. Many studies reported that interferon reduces the risk of hepatocellular carcinoma in patients with chronic hepatitis...

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Autores principales: Derbala, Moutaz, Amer, Aliaa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827147/
https://www.ncbi.nlm.nih.gov/pubmed/20181199
http://dx.doi.org/10.4076/1757-1626-2-7927
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author Derbala, Moutaz
Amer, Aliaa
author_facet Derbala, Moutaz
Amer, Aliaa
author_sort Derbala, Moutaz
collection PubMed
description Genotype 4 Hepatitis C virus represents approximately 20% of global Hepatitis C virus infection and is the source of a considerable burden to health-care providers across the globe. Many studies reported that interferon reduces the risk of hepatocellular carcinoma in patients with chronic hepatitis C. Hereby, we are reporting two cases of hepatocellular carcinoma in Hepatitis C virus-genotype 4 after complete viral eradication and in absence of cirrhosis. We aim to highlight the possible direct oncogenic effect of Hepatitis C virus-genotype 4, particularly with concomitant bilharzial infection and the importance of life-log follow up of these patients even in absence of cirrhosis.
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spelling pubmed-28271472010-02-24 Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports Derbala, Moutaz Amer, Aliaa Cases J Case Report Genotype 4 Hepatitis C virus represents approximately 20% of global Hepatitis C virus infection and is the source of a considerable burden to health-care providers across the globe. Many studies reported that interferon reduces the risk of hepatocellular carcinoma in patients with chronic hepatitis C. Hereby, we are reporting two cases of hepatocellular carcinoma in Hepatitis C virus-genotype 4 after complete viral eradication and in absence of cirrhosis. We aim to highlight the possible direct oncogenic effect of Hepatitis C virus-genotype 4, particularly with concomitant bilharzial infection and the importance of life-log follow up of these patients even in absence of cirrhosis. BioMed Central 2009-09-15 /pmc/articles/PMC2827147/ /pubmed/20181199 http://dx.doi.org/10.4076/1757-1626-2-7927 Text en Copyright ©2009 Derbala and Amer; licensee Cases Network Ltd. licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Derbala, Moutaz
Amer, Aliaa
Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports
title Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports
title_full Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports
title_fullStr Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports
title_full_unstemmed Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports
title_short Hepatocellular carcinoma in Hepatitis C genotype 4 after viral clearance and in absence of cirrhosis: two case reports
title_sort hepatocellular carcinoma in hepatitis c genotype 4 after viral clearance and in absence of cirrhosis: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827147/
https://www.ncbi.nlm.nih.gov/pubmed/20181199
http://dx.doi.org/10.4076/1757-1626-2-7927
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AT ameraliaa hepatocellularcarcinomainhepatitiscgenotype4afterviralclearanceandinabsenceofcirrhosistwocasereports

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