Tuberous sclerosis with visceral leishmaniasis: a case report

INTRODUCTION: Visceral leishmaniasis, a tropical infectious disease, is a major public health problem in India. Tuberous sclerosis, a congenital neuro-ectodermosis, is an uncommon disease which requires life long treatment. CASE PRESENTATION: A 15-year-old Indian patient, presented to the outpatient...

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Detalles Bibliográficos
Autores principales: Pandey, Krishna, Sinha, Prabhat K, Das, Vidyanand R, Kumar, Nawin, Bimal, Sanjiva, Verma, Rakesh B, Verma, Neena, Lal, Chandra S, Topno, Roshan K, Siddiqui, NA, Singh, Dharmendra, Das, Pradeep
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827167/
http://dx.doi.org/10.4076/1752-1947-3-9027
Descripción
Sumario:INTRODUCTION: Visceral leishmaniasis, a tropical infectious disease, is a major public health problem in India. Tuberous sclerosis, a congenital neuro-ectodermosis, is an uncommon disease which requires life long treatment. CASE PRESENTATION: A 15-year-old Indian patient, presented to the outpatient department of our institute with a high-grade fever for two months, splenomegaly and a history of generalized tonic-clonic convulsions since childhood. The clinical and laboratory findings suggested visceral leishmaniasis with tuberous sclerosis. The patient was treated with miltefosine and antiepileptics. CONCLUSION: The patient responded well and in a follow up six months after presentation, she was found free of visceral leishmaniasis and seizures. Diagnosis and treatment of this rare combination of diseases is difficult.

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