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Diet-Induced Obesity Prevents Interstitial Dispersion of Insulin in Skeletal Muscle
OBJECTIVE: Obesity causes insulin resistance, which has been interpreted as reduced downstream insulin signaling. However, changes in access of insulin to sensitive tissues such as skeletal muscle may also play a role. Insulin injected directly into skeletal muscle diffuses rapidly through the inter...
Autores principales: | Kolka, Cathryn M., Harrison, L. Nicole, Lottati, Maya, Chiu, Jenny D., Kirkman, Erlinda L., Bergman, Richard N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827487/ https://www.ncbi.nlm.nih.gov/pubmed/19959760 http://dx.doi.org/10.2337/db09-0839 |
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